Emflaza

Deflazacort

Emflaza is a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients at the age of 5 and older.
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Package Per pill Price Savings Order
180 tablet
C$ 1.04
C$ 186.53C$ 1.04
C$ 329.78
120 tablet
C$ 1.20
C$ 143.47C$ 1.20
C$ 200.74
90 tablet
C$ 1.43
C$ 129.11C$ 1.43
C$ 129.04
60 tablet
C$ 1.79
C$ 107.58C$ 1.79
C$ 64.52
30 tablet
C$ 2.87
C$ 86.05C$ 2.87
Package Per pill Price Savings Order
120 tablet
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C$ 6.58
C$ 789.40C$ 6.58
C$ 143.25
90 tablet
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C$ 6.94
C$ 624.33C$ 6.94
C$ 75.16
60 tablet
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C$ 7.18
C$ 430.55C$ 7.18
C$ 35.78
36 tablet
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C$ 7.57
C$ 272.65C$ 7.57
C$ 7.14
24 tablet
C$ 7.77
C$ 186.53C$ 7.77
Package Per pill Price Savings Order
90 tablet
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C$ 7.97
C$ 717.63C$ 7.97
C$ 143.34
60 tablet
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C$ 8.61
C$ 516.67C$ 8.61
C$ 57.31
36 tablet
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C$ 9.17
C$ 330.07C$ 9.17
C$ 14.32
24 tablet
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C$ 9.57
C$ 229.59C$ 9.57
Emflaza

Brand(s)

Manufacturer

  • Lupin

Disease(s)

  • Duchenne Muscular Dystrophy / DMD

Deflazacort tablets

What is this medicine?

Deflazacort a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients 5 years of age and older.

What should I tell my health care providers before I take this medicine?

They need to know if you have any of these conditions:

  • Hypersensitivity to deflazacort;
  • Alterations in Endocrine Function: Hypothalamic-pituitary-adrenal axis suppression, Cushing’s syndrome, and hyperglycemia;
  • Immunosuppression and Increased Risk of Infection: Increased risk of new, exacerbation, dissemination, or reactivation of latent infections, which can be severe and at times fatal;
  • Alterations in Cardiovascular/Renal Function: elevated blood pressure and sodium, and for decreased potassium level;
  • Gastrointestinal Perforation: GI disorders;
  • Behavioral and Mood Disturbances: euphoria, insomnia, mood swings, personality changes, severe depression, and psychosis;
  • Effects on Bones: decreases in bone mineral density;
  • Serious Skin Rashes;
  • Ophthalmic Effects: May include cataracts, infections, and glaucoma;
  • Vaccination: Do not administer live or live attenuated vaccines to patients receiving immunosuppressive doses of corticosteroids.

How should I use this medicine?

The recommended once-daily dosage is approximately 0.9 mg/kg/day administered orally. Discontinue gradually when administered for more than a few day..

What may interact with this medicine?

  • Moderate or strong CYP3A4 inhibitors: Give one third of the recommended dosage;
  • Avoid use of moderate or strong CYP3A4 inducers, as they may reduce efficacy.

What side effects may I notice from this medicine?

The most common adverse reactions are Cushingoid appearance, weight increased, increased appetite, upper respiratory tract infection, cough, pollakiuria, hirsutism, central obesity, and nasopharyngitis.