Emflaza

Deflazacort

Emflaza is a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients at the age of 5 and older.
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Package Per pill Price Savings Order
180 tablet
C$ 1.02
C$ 184.18C$ 1.02
C$ 325.62
120 tablet
C$ 1.18
C$ 141.66C$ 1.18
C$ 198.21
90 tablet
C$ 1.42
C$ 127.49C$ 1.42
C$ 127.42
60 tablet
C$ 1.77
C$ 106.23C$ 1.77
C$ 63.71
30 tablet
C$ 2.83
C$ 84.97C$ 2.83
Package Per pill Price Savings Order
120 tablet
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C$ 6.50
C$ 779.44C$ 6.50
C$ 141.45
90 tablet
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C$ 6.85
C$ 616.45C$ 6.85
C$ 74.21
60 tablet
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C$ 7.09
C$ 425.12C$ 7.09
C$ 35.33
36 tablet
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C$ 7.48
C$ 269.22C$ 7.48
C$ 7.05
24 tablet
C$ 7.67
C$ 184.18C$ 7.67
Package Per pill Price Savings Order
90 tablet
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C$ 7.87
C$ 708.58C$ 7.87
C$ 141.54
60 tablet
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C$ 8.50
C$ 510.16C$ 8.50
C$ 56.59
36 tablet
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C$ 9.05
C$ 325.91C$ 9.05
C$ 14.14
24 tablet
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C$ 9.45
C$ 226.70C$ 9.45
Emflaza

Brand(s)

Manufacturer

  • Lupin

Disease(s)

  • Duchenne Muscular Dystrophy / DMD

Deflazacort tablets

What is this medicine?

Deflazacort a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients 5 years of age and older.

What should I tell my health care providers before I take this medicine?

They need to know if you have any of these conditions:

  • Hypersensitivity to deflazacort;
  • Alterations in Endocrine Function: Hypothalamic-pituitary-adrenal axis suppression, Cushing’s syndrome, and hyperglycemia;
  • Immunosuppression and Increased Risk of Infection: Increased risk of new, exacerbation, dissemination, or reactivation of latent infections, which can be severe and at times fatal;
  • Alterations in Cardiovascular/Renal Function: elevated blood pressure and sodium, and for decreased potassium level;
  • Gastrointestinal Perforation: GI disorders;
  • Behavioral and Mood Disturbances: euphoria, insomnia, mood swings, personality changes, severe depression, and psychosis;
  • Effects on Bones: decreases in bone mineral density;
  • Serious Skin Rashes;
  • Ophthalmic Effects: May include cataracts, infections, and glaucoma;
  • Vaccination: Do not administer live or live attenuated vaccines to patients receiving immunosuppressive doses of corticosteroids.

How should I use this medicine?

The recommended once-daily dosage is approximately 0.9 mg/kg/day administered orally. Discontinue gradually when administered for more than a few day..

What may interact with this medicine?

  • Moderate or strong CYP3A4 inhibitors: Give one third of the recommended dosage;
  • Avoid use of moderate or strong CYP3A4 inducers, as they may reduce efficacy.

What side effects may I notice from this medicine?

The most common adverse reactions are Cushingoid appearance, weight increased, increased appetite, upper respiratory tract infection, cough, pollakiuria, hirsutism, central obesity, and nasopharyngitis.