Disulfiram

Brand(s)

Manufacturer

• Intas Pharmaceuticals Ltd.

Disease(s)

• Alcoholism

Disulfiram tablet

What is this medicine?

DISULFIRAM can help patients with an alcohol abuse problem not to drink alcohol. When taken with alcohol, this medicine produces unpleasant effects. This medicine is part of a recovery program that includes medical supervision and counseling. It is not a cure.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of the following conditions:

• brain damage
• diabetes
• heart disease
• kidney disease
• liver disease
• psychotic disease
• recently exposure to alcohol or any product that contains alcohol
• seizures
• taking metronidazole or paraldehyde
• under-active thyroid
• an unusual or allergic reaction to disulfiram, pesticides or rubber products, other medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

How should I use this medicine?

Take this medicine by mouth with a full glass of water. You must never take this medicine within 12 hours of taking any alcohol. The tablets can be crushed and mixed with liquid before taking. Take your medicine at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on your doctor's advice.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

• alcohol or any product that contains alcohol
• amprenavir
• cocaine
• lopinavir; ritonavir
• metronidazole
• oral solutions of ritonavir or sertraline
• paclitaxel
• paraldehyde
• tranylcypromine

This medicine may also interact with the following medications:

• isoniazid
• medicines that treat or prevent blood clots like warfarin
• phenytoin

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress.

Never take this medicine if you have been drinking alcohol. Make sure that family members or others in your household know about this medicine and what to do in an emergency. When this medicine is taken with even small amounts of alcohol, it will produce very unpleasant effects. You may get a throbbing headache, flushing, vomiting, weakness and chest pain. Breathing and heart problems, seizures and death can occur. This medicine can react with alcohol even 14 days after you take your last dose.

Never take products or use toiletries that contain alcohol. Always read labels carefully. Many cough syrups, liquid pain medications, tonics, mouthwashes, after shave lotions, colognes, liniments, vinegar's, and sauces contain alcohol.

Wear a medical identification bracelet or chain to say you are taking this medicine. Carry an identification card with your name, name and dose of medicine being used, and name and phone number of your doctor and/or person to contact in an emergency.

What side effects may I notice from this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
• changes in vision
• confusion, disorientation, irritability
• dark urine
• general ill feeling or flu-like symptoms
• loss of appetite, nausea
• loss of contact with reality
• numbness, pain or tingling
• right upper belly pain
• unusually weak or tired
• yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• change in sex drive or performance
• dizziness
• drowsy, tired
• headache
• metallic or garlic taste
• nausea, vomiting

This list may not describe all possible side effects.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Keep in a tight light resistant container. Throw away any unused medicine after the expiration date.