Emflaza

Deflazacort

Emflaza is a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients at the age of 5 and older.

Package	Per pill	Price	Savings
180 tablet	£ 34.12	£ 6142.35£ 34.12	£ 10859.59
120 tablet	£ 39.37	£ 4724.34£ 39.37	£ 6610.29
90 tablet	£ 47.24	£ 4251.67£ 47.24	£ 4249.30
60 tablet	£ 59.04	£ 3542.66£ 59.04	£ 2124.65
30 tablet	£ 94.46	£ 2833.66£ 94.46

Package	Per pill	Price	Savings
120 tablet Free AirMail shipping Hot	£ 216.62	£ 25994.49£ 216.62	£ 4717.25
90 tablet Free AirMail shipping Hot	£ 228.43	£ 20558.78£ 228.43	£ 2475.02
60 tablet Free AirMail shipping Hot	£ 236.30	£ 14177.74£ 236.30	£ 1178.13
36 tablet Free AirMail shipping Hot	£ 249.40	£ 8978.37£ 249.40	£ 235.15
24 tablet	£ 255.93	£ 6142.35£ 255.93

Package	Per pill	Price	Savings
90 tablet Free AirMail shipping Hot	£ 262.57	£ 23631.14£ 262.57	£ 4720.20
60 tablet Free AirMail shipping Hot	£ 283.56	£ 17013.76£ 283.56	£ 1887.13
36 tablet Free AirMail shipping Hot	£ 301.92	£ 10869.05£ 301.92	£ 471.49
24 tablet Free AirMail shipping Hot	£ 315.01	£ 7560.36£ 315.01

Brand(s)

Manufacturer

Lupin

Disease(s)

Duchenne Muscular Dystrophy / DMD

Deflazacort tablets

What is this medicine?

Deflazacort a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients 5 years of age and older.

What should I tell my health care providers before I take this medicine?

They need to know if you have any of these conditions:

Hypersensitivity to deflazacort;
Alterations in Endocrine Function: Hypothalamic-pituitary-adrenal axis suppression, Cushing’s syndrome, and hyperglycemia;
Immunosuppression and Increased Risk of Infection: Increased risk of new, exacerbation, dissemination, or reactivation of latent infections, which can be severe and at times fatal;
Alterations in Cardiovascular/Renal Function: elevated blood pressure and sodium, and for decreased potassium level;
Gastrointestinal Perforation: GI disorders;
Behavioral and Mood Disturbances: euphoria, insomnia, mood swings, personality changes, severe depression, and psychosis;
Effects on Bones: decreases in bone mineral density;
Serious Skin Rashes;
Ophthalmic Effects: May include cataracts, infections, and glaucoma;
Vaccination: Do not administer live or live attenuated vaccines to patients receiving immunosuppressive doses of corticosteroids.

How should I use this medicine?

The recommended once-daily dosage is approximately 0.9 mg/kg/day administered orally. Discontinue gradually when administered for more than a few day..

What may interact with this medicine?

Moderate or strong CYP3A4 inhibitors: Give one third of the recommended dosage;
Avoid use of moderate or strong CYP3A4 inducers, as they may reduce efficacy.

What side effects may I notice from this medicine?

The most common adverse reactions are Cushingoid appearance, weight increased, increased appetite, upper respiratory tract infection, cough, pollakiuria, hirsutism, central obesity, and nasopharyngitis.

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