Emflaza

Deflazacort

Emflaza is a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients at the age of 5 and older.

Package	Per pill	Price	Savings
180 tablet	£ 35.84	£ 6451.15£ 35.84	£ 11405.55
120 tablet	£ 41.35	£ 4961.85£ 41.35	£ 6942.62
90 tablet	£ 49.62	£ 4465.41£ 49.62	£ 4462.93
60 tablet	£ 62.01	£ 3720.77£ 62.01	£ 2231.47
30 tablet	£ 99.20	£ 2976.12£ 99.20

Package	Per pill	Price	Savings
120 tablet Free AirMail shipping Hot	£ 227.51	£ 27301.33£ 227.51	£ 4954.40
90 tablet Free AirMail shipping Hot	£ 239.92	£ 21592.35£ 239.92	£ 2599.45
60 tablet Free AirMail shipping Hot	£ 248.18	£ 14890.51£ 248.18	£ 1237.36
36 tablet Free AirMail shipping Hot	£ 261.94	£ 9429.74£ 261.94	£ 246.98
24 tablet	£ 268.80	£ 6451.15£ 268.80

Package	Per pill	Price	Savings
90 tablet Free AirMail shipping Hot	£ 275.77	£ 24819.17£ 275.77	£ 4957.50
60 tablet Free AirMail shipping Hot	£ 297.82	£ 17869.11£ 297.82	£ 1982.01
36 tablet Free AirMail shipping Hot	£ 317.10	£ 11415.48£ 317.10	£ 495.19
24 tablet Free AirMail shipping Hot	£ 330.85	£ 7940.45£ 330.85

Brand(s)

Manufacturer

Lupin

Disease(s)

Duchenne Muscular Dystrophy / DMD

Deflazacort tablets

What is this medicine?

Deflazacort a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients 5 years of age and older.

What should I tell my health care providers before I take this medicine?

They need to know if you have any of these conditions:

Hypersensitivity to deflazacort;
Alterations in Endocrine Function: Hypothalamic-pituitary-adrenal axis suppression, Cushing’s syndrome, and hyperglycemia;
Immunosuppression and Increased Risk of Infection: Increased risk of new, exacerbation, dissemination, or reactivation of latent infections, which can be severe and at times fatal;
Alterations in Cardiovascular/Renal Function: elevated blood pressure and sodium, and for decreased potassium level;
Gastrointestinal Perforation: GI disorders;
Behavioral and Mood Disturbances: euphoria, insomnia, mood swings, personality changes, severe depression, and psychosis;
Effects on Bones: decreases in bone mineral density;
Serious Skin Rashes;
Ophthalmic Effects: May include cataracts, infections, and glaucoma;
Vaccination: Do not administer live or live attenuated vaccines to patients receiving immunosuppressive doses of corticosteroids.

How should I use this medicine?

The recommended once-daily dosage is approximately 0.9 mg/kg/day administered orally. Discontinue gradually when administered for more than a few day..

What may interact with this medicine?

Moderate or strong CYP3A4 inhibitors: Give one third of the recommended dosage;
Avoid use of moderate or strong CYP3A4 inducers, as they may reduce efficacy.

What side effects may I notice from this medicine?

The most common adverse reactions are Cushingoid appearance, weight increased, increased appetite, upper respiratory tract infection, cough, pollakiuria, hirsutism, central obesity, and nasopharyngitis.

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