Emflaza

Deflazacort

Emflaza is a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients at the age of 5 and older.

Package	Per pill	Price	Savings
180 tablet	£ 36.74	£ 6614.09£ 36.74	£ 11693.63
120 tablet	£ 42.39	£ 5087.18£ 42.39	£ 7117.97
90 tablet	£ 50.87	£ 4578.20£ 50.87	£ 4575.66
60 tablet	£ 63.58	£ 3814.75£ 63.58	£ 2287.83
30 tablet	£ 101.71	£ 3051.29£ 101.71

Package	Per pill	Price	Savings
120 tablet Free AirMail shipping Hot	£ 233.26	£ 27990.92£ 233.26	£ 5079.54
90 tablet Free AirMail shipping Hot	£ 245.97	£ 22137.74£ 245.97	£ 2665.10
60 tablet Free AirMail shipping Hot	£ 254.44	£ 15266.62£ 254.44	£ 1268.61
36 tablet Free AirMail shipping Hot	£ 268.55	£ 9667.92£ 268.55	£ 253.21
24 tablet	£ 275.59	£ 6614.09£ 275.59

Package	Per pill	Price	Savings
90 tablet Free AirMail shipping Hot	£ 282.73	£ 25446.06£ 282.73	£ 5082.72
60 tablet Free AirMail shipping Hot	£ 305.34	£ 18320.45£ 305.34	£ 2032.07
36 tablet Free AirMail shipping Hot	£ 325.11	£ 11703.81£ 325.11	£ 507.70
24 tablet Free AirMail shipping Hot	£ 339.21	£ 8141.01£ 339.21

Brand(s)

Manufacturer

Lupin

Disease(s)

Duchenne Muscular Dystrophy / DMD

Deflazacort tablets

What is this medicine?

Deflazacort a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients 5 years of age and older.

What should I tell my health care providers before I take this medicine?

They need to know if you have any of these conditions:

Hypersensitivity to deflazacort;
Alterations in Endocrine Function: Hypothalamic-pituitary-adrenal axis suppression, Cushing’s syndrome, and hyperglycemia;
Immunosuppression and Increased Risk of Infection: Increased risk of new, exacerbation, dissemination, or reactivation of latent infections, which can be severe and at times fatal;
Alterations in Cardiovascular/Renal Function: elevated blood pressure and sodium, and for decreased potassium level;
Gastrointestinal Perforation: GI disorders;
Behavioral and Mood Disturbances: euphoria, insomnia, mood swings, personality changes, severe depression, and psychosis;
Effects on Bones: decreases in bone mineral density;
Serious Skin Rashes;
Ophthalmic Effects: May include cataracts, infections, and glaucoma;
Vaccination: Do not administer live or live attenuated vaccines to patients receiving immunosuppressive doses of corticosteroids.

How should I use this medicine?

The recommended once-daily dosage is approximately 0.9 mg/kg/day administered orally. Discontinue gradually when administered for more than a few day..

What may interact with this medicine?

Moderate or strong CYP3A4 inhibitors: Give one third of the recommended dosage;
Avoid use of moderate or strong CYP3A4 inducers, as they may reduce efficacy.

What side effects may I notice from this medicine?

The most common adverse reactions are Cushingoid appearance, weight increased, increased appetite, upper respiratory tract infection, cough, pollakiuria, hirsutism, central obesity, and nasopharyngitis.

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