Emflaza

Deflazacort

Emflaza is a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients at the age of 5 and older.
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Package Per pill Price Savings Order
180 tablet
£ 0.57
£ 103.08£ 0.57
£ 182.24
120 tablet
£ 0.66
£ 79.28£ 0.66
£ 110.93
90 tablet
£ 0.79
£ 71.35£ 0.79
£ 71.31
60 tablet
£ 0.99
£ 59.45£ 0.99
£ 35.65
30 tablet
£ 1.59
£ 47.55£ 1.59
Package Per pill Price Savings Order
120 tablet
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£ 3.64
£ 436.22£ 3.64
£ 79.16
90 tablet
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£ 3.83
£ 345.00£ 3.83
£ 41.53
60 tablet
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£ 3.97
£ 237.92£ 3.97
£ 19.77
36 tablet
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£ 4.19
£ 150.67£ 4.19
£ 3.95
24 tablet
£ 4.29
£ 103.08£ 4.29
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90 tablet
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£ 4.41
£ 396.56£ 4.41
£ 79.21
60 tablet
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£ 4.76
£ 285.51£ 4.76
£ 31.67
36 tablet
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£ 5.07
£ 182.40£ 5.07
£ 7.91
24 tablet
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£ 5.29
£ 126.87£ 5.29
Emflaza

Brand(s)

Manufacturer

  • Lupin

Disease(s)

  • Duchenne Muscular Dystrophy / DMD

Deflazacort tablets

What is this medicine?

Deflazacort a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients 5 years of age and older.

What should I tell my health care providers before I take this medicine?

They need to know if you have any of these conditions:

  • Hypersensitivity to deflazacort;
  • Alterations in Endocrine Function: Hypothalamic-pituitary-adrenal axis suppression, Cushing’s syndrome, and hyperglycemia;
  • Immunosuppression and Increased Risk of Infection: Increased risk of new, exacerbation, dissemination, or reactivation of latent infections, which can be severe and at times fatal;
  • Alterations in Cardiovascular/Renal Function: elevated blood pressure and sodium, and for decreased potassium level;
  • Gastrointestinal Perforation: GI disorders;
  • Behavioral and Mood Disturbances: euphoria, insomnia, mood swings, personality changes, severe depression, and psychosis;
  • Effects on Bones: decreases in bone mineral density;
  • Serious Skin Rashes;
  • Ophthalmic Effects: May include cataracts, infections, and glaucoma;
  • Vaccination: Do not administer live or live attenuated vaccines to patients receiving immunosuppressive doses of corticosteroids.

How should I use this medicine?

The recommended once-daily dosage is approximately 0.9 mg/kg/day administered orally. Discontinue gradually when administered for more than a few day..

What may interact with this medicine?

  • Moderate or strong CYP3A4 inhibitors: Give one third of the recommended dosage;
  • Avoid use of moderate or strong CYP3A4 inducers, as they may reduce efficacy.

What side effects may I notice from this medicine?

The most common adverse reactions are Cushingoid appearance, weight increased, increased appetite, upper respiratory tract infection, cough, pollakiuria, hirsutism, central obesity, and nasopharyngitis.