Emflaza

Deflazacort

Emflaza is a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients at the age of 5 and older.
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180 tablet
Rp 11797.61
Rp 2123569.22Rp 11797.61
Rp 3754444.23
120 tablet
Rp 13611.05
Rp 1633326.23Rp 13611.05
Rp 2285349.41
90 tablet
Rp 16332.35
Rp 1469911.90Rp 16332.35
Rp 1469094.83
60 tablet
Rp 20413.17
Rp 1224790.40Rp 20413.17
Rp 734547.41
30 tablet
Rp 32655.63
Rp 979668.91Rp 32655.63
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120 tablet
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Rp 74891.43
Rp 8986971.08Rp 74891.43
Rp 1630875.01
90 tablet
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Rp 78974.51
Rp 7107706.28Rp 78974.51
Rp 855678.29
60 tablet
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Rp 81693.55
Rp 4901612.83Rp 81693.55
Rp 407310.22
36 tablet
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Rp 86223.76
Rp 3104055.20Rp 86223.76
Rp 81298.63
24 tablet
Rp 88482.05
Rp 2123569.22Rp 88482.05
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90 tablet
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Rp 90776.66
Rp 8169899.43Rp 90776.66
Rp 1631896.35
60 tablet
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Rp 98034.98
Rp 5882098.81Rp 98034.98
Rp 652431.71
36 tablet
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Rp 104380.90
Rp 3757712.52Rp 104380.90
Rp 163005.79
24 tablet
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Rp 108908.84
Rp 2613812.21Rp 108908.84
Emflaza

Brand(s)

Manufacturer

  • Lupin

Disease(s)

  • Duchenne Muscular Dystrophy / DMD

Deflazacort tablets

What is this medicine?

Deflazacort a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients 5 years of age and older.

What should I tell my health care providers before I take this medicine?

They need to know if you have any of these conditions:

  • Hypersensitivity to deflazacort;
  • Alterations in Endocrine Function: Hypothalamic-pituitary-adrenal axis suppression, Cushing’s syndrome, and hyperglycemia;
  • Immunosuppression and Increased Risk of Infection: Increased risk of new, exacerbation, dissemination, or reactivation of latent infections, which can be severe and at times fatal;
  • Alterations in Cardiovascular/Renal Function: elevated blood pressure and sodium, and for decreased potassium level;
  • Gastrointestinal Perforation: GI disorders;
  • Behavioral and Mood Disturbances: euphoria, insomnia, mood swings, personality changes, severe depression, and psychosis;
  • Effects on Bones: decreases in bone mineral density;
  • Serious Skin Rashes;
  • Ophthalmic Effects: May include cataracts, infections, and glaucoma;
  • Vaccination: Do not administer live or live attenuated vaccines to patients receiving immunosuppressive doses of corticosteroids.

How should I use this medicine?

The recommended once-daily dosage is approximately 0.9 mg/kg/day administered orally. Discontinue gradually when administered for more than a few day..

What may interact with this medicine?

  • Moderate or strong CYP3A4 inhibitors: Give one third of the recommended dosage;
  • Avoid use of moderate or strong CYP3A4 inducers, as they may reduce efficacy.

What side effects may I notice from this medicine?

The most common adverse reactions are Cushingoid appearance, weight increased, increased appetite, upper respiratory tract infection, cough, pollakiuria, hirsutism, central obesity, and nasopharyngitis.