Emflaza

Deflazacort

Emflaza is a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients at the age of 5 and older.
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180 tablet
Rp 11705.82
Rp 2107048.03Rp 11705.82
Rp 3725234.97
120 tablet
Rp 13505.16
Rp 1620619.09Rp 13505.16
Rp 2267569.58
90 tablet
Rp 16205.29
Rp 1458476.11Rp 16205.29
Rp 1457665.39
60 tablet
Rp 20254.36
Rp 1215261.64Rp 20254.36
Rp 728832.70
30 tablet
Rp 32401.57
Rp 972047.17Rp 32401.57
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120 tablet
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Rp 74308.78
Rp 8917053.19Rp 74308.78
Rp 1618186.94
90 tablet
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Rp 78360.10
Rp 7052408.92Rp 78360.10
Rp 849021.18
60 tablet
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Rp 81057.98
Rp 4863478.69Rp 81057.98
Rp 404141.38
36 tablet
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Rp 85552.94
Rp 3079905.91Rp 85552.94
Rp 80666.13
24 tablet
Rp 87793.67
Rp 2107048.03Rp 87793.67
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90 tablet
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Rp 90070.43
Rp 8106338.29Rp 90070.43
Rp 1619200.33
60 tablet
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Rp 97272.28
Rp 5836336.57Rp 97272.28
Rp 647355.85
36 tablet
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Rp 103568.83
Rp 3728477.83Rp 103568.83
Rp 161737.62
24 tablet
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Rp 108061.54
Rp 2593476.97Rp 108061.54
Emflaza

Brand(s)

Manufacturer

  • Lupin

Disease(s)

  • Duchenne Muscular Dystrophy / DMD

Deflazacort tablets

What is this medicine?

Deflazacort a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients 5 years of age and older.

What should I tell my health care providers before I take this medicine?

They need to know if you have any of these conditions:

  • Hypersensitivity to deflazacort;
  • Alterations in Endocrine Function: Hypothalamic-pituitary-adrenal axis suppression, Cushing’s syndrome, and hyperglycemia;
  • Immunosuppression and Increased Risk of Infection: Increased risk of new, exacerbation, dissemination, or reactivation of latent infections, which can be severe and at times fatal;
  • Alterations in Cardiovascular/Renal Function: elevated blood pressure and sodium, and for decreased potassium level;
  • Gastrointestinal Perforation: GI disorders;
  • Behavioral and Mood Disturbances: euphoria, insomnia, mood swings, personality changes, severe depression, and psychosis;
  • Effects on Bones: decreases in bone mineral density;
  • Serious Skin Rashes;
  • Ophthalmic Effects: May include cataracts, infections, and glaucoma;
  • Vaccination: Do not administer live or live attenuated vaccines to patients receiving immunosuppressive doses of corticosteroids.

How should I use this medicine?

The recommended once-daily dosage is approximately 0.9 mg/kg/day administered orally. Discontinue gradually when administered for more than a few day..

What may interact with this medicine?

  • Moderate or strong CYP3A4 inhibitors: Give one third of the recommended dosage;
  • Avoid use of moderate or strong CYP3A4 inducers, as they may reduce efficacy.

What side effects may I notice from this medicine?

The most common adverse reactions are Cushingoid appearance, weight increased, increased appetite, upper respiratory tract infection, cough, pollakiuria, hirsutism, central obesity, and nasopharyngitis.