Emflaza

Deflazacort

Emflaza é um corticosteróide indicado para o tratamento da distrofia muscular de Duchenne (DMD) em pacientes com idade inferior a 5 anos e mais velhos.
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180 tablet
R$ 4.47
R$ 804.29R$ 4.47
R$ 1421.97
120 tablet
R$ 5.16
R$ 618.61R$ 5.16
R$ 865.56
90 tablet
R$ 6.19
R$ 556.72R$ 6.19
R$ 556.41
60 tablet
R$ 7.73
R$ 463.88R$ 7.73
R$ 278.20
30 tablet
R$ 12.37
R$ 371.04R$ 12.37
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120 tablet
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R$ 28.36
R$ 3403.75R$ 28.36
R$ 617.68
90 tablet
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R$ 29.91
R$ 2691.99R$ 29.91
R$ 324.08
60 tablet
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R$ 30.94
R$ 1856.45R$ 30.94
R$ 154.27
36 tablet
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R$ 32.66
R$ 1175.64R$ 32.66
R$ 30.79
24 tablet
R$ 33.51
R$ 804.29R$ 33.51
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90 tablet
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R$ 34.38
R$ 3094.29R$ 34.38
R$ 618.07
60 tablet
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R$ 37.13
R$ 2227.80R$ 37.13
R$ 247.10
36 tablet
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R$ 39.53
R$ 1423.21R$ 39.53
R$ 61.74
24 tablet
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R$ 41.25
R$ 989.96R$ 41.25
Emflaza

Marca(s)

Fabricante

  • Lupin

Diseases

  • Duchenne Muscular Dystrophy / DMD

Deflazacort tablets

What is this medicine?

Deflazacort a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients 5 years of age and older.

What should I tell my health care providers before I take this medicine?

They need to know if you have any of these conditions:

  • Hypersensitivity to deflazacort;
  • Alterations in Endocrine Function: Hypothalamic-pituitary-adrenal axis suppression, Cushing’s syndrome, and hyperglycemia;
  • Immunosuppression and Increased Risk of Infection: Increased risk of new, exacerbation, dissemination, or reactivation of latent infections, which can be severe and at times fatal;
  • Alterations in Cardiovascular/Renal Function: elevated blood pressure and sodium, and for decreased potassium level;
  • Gastrointestinal Perforation: GI disorders;
  • Behavioral and Mood Disturbances: euphoria, insomnia, mood swings, personality changes, severe depression, and psychosis;
  • Effects on Bones: decreases in bone mineral density;
  • Serious Skin Rashes;
  • Ophthalmic Effects: May include cataracts, infections, and glaucoma;
  • Vaccination: Do not administer live or live attenuated vaccines to patients receiving immunosuppressive doses of corticosteroids.

How should I use this medicine?

The recommended once-daily dosage is approximately 0.9 mg/kg/day administered orally. Discontinue gradually when administered for more than a few day..

What may interact with this medicine?

  • Moderate or strong CYP3A4 inhibitors: Give one third of the recommended dosage;
  • Avoid use of moderate or strong CYP3A4 inducers, as they may reduce efficacy.

What side effects may I notice from this medicine?

The most common adverse reactions are Cushingoid appearance, weight increased, increased appetite, upper respiratory tract infection, cough, pollakiuria, hirsutism, central obesity, and nasopharyngitis.